While many SUVs will accommodate large dogs, the Ford Flex ranks high on the list because of its people-friendly qualities. Its low ride height means stepping in and out is easy for passengers as well as their four-legged friends, while its refrigerated console comes in handy for keeping drinks or snacks cool for its occupants, whether human or canine. The Ford Flex seats up to seven passengers, with a third row seat that is comfortable for teens or adults. Though you'll probably need to keep the third row folded if you are traveling with a large-breed dog. The new 335-horsepower, 3.5-liter EcoBoost engine offers V-8 power with V-6-like fuel economy, a strong selling point if you like find yourself on the road frequently.